The major goals of Multiple Sclerosis (MS) genetic research are to identify the genes that influence disease susceptibility and the progression of symptoms. Knowing what these genes are and what they do will help researchers to understand the causes of MS and its progression. Armed with this knowledge we will be in better position to predict a person’s prognosis and design new and more effective treatments.
The Australian MS genetics research effort focuses on identifying the genes that influence the progression of MS and lead to relapses. The project is broken into three components:
Phase 1 - was the development of the MS Gene Bank. This has been successful in pooling Australia's MS samples to increase the reliability of results from MS genetics studies.
Phase 2 - saw the first samples undergo gene-mapping and analysis at the University of Queensland in early 2008. The MS Gene Bank continues to accept samples from People with MS.
Phase 3 - measures the amount of gene product in blood from samples from People with Primary Progressive MS, Relapsing Remitting MS, Secondary Progressive MS and People without MS.
The MS genetics team is a national, collaborative effort between a multi-disciplinary team of neurologists, geneticists, bioinformaticians and molecular biologists. MSRA has a secretariat function.
MS Research Australia is grateful for contributions from the John T Reid Charitable Trusts, the Trish MS Research Foundation, individual donors and an Australian Research Council linkage grant, for making this major collaboration possible.
For some of the recent progress made by the ANZgene team, please visit the following pages:
If you have MS, consider becoming involved with the MS Gene Bank.
Please call your local clinical contact for more information
|Location||Clinical Contact||Phone Number|
|Sydney||Theresa Burke, Westmead Hospital||02 9845 7997|
|Newcastle||Susan Agland, John Hunter Hospital||02 4985 5880|
|Victoria||Mary Tanner, Royal Melbourne Hospital||03 9342 7041|
|Tasmania||Carol Hurst, Menzies Research Institute||07 5678 0750|
|Queensland||Susan Freeman, Griffith University||07 5678 0750|